For most CBD e-liquids, a 70/30 or 50/50 (PG/VG) base is the recommended choice, as it balances cannabinoid dissolution and flavor delivery. A 30/70 ratio is better suited to direct lung vaping and those who enjoy dense clouds. One last point worth noting: always check the exact composition of the product, as some liquids contain undeclared additives that increase the risks associated with inhalation.


In short:

  • The ideal PG/VG ratio for CBD is generally between 50/50 and 70/30, in order to ensure good dissolution of the cannabinoid and faithful reproduction of the aromas.
  • A 30/70 ratio favors the production of dense vapor suitable for direct lung hits, but can reduce the lifespan of the coils and increase the risk of irritation.
  • Since CBD is more soluble in PG, a base too rich in VG can lead to crystallization or degradation of the product, impacting dose consistency.
  • The recommended starting concentration is between 5 and 15 mg/ml, while experienced users can opt for doses up to 30 mg/ml or more, progressing in stages.
  • Before purchase, verification of independent certificates of analysis guarantees product conformity and limits risks related to additives or poor formulation.

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Table of Contents

PG, VG, CBD: Understanding the role of each base

Propylene glycol (PG) and vegetable glycerin (VG) form the base of all e-liquids, including those enriched with CBD. These two colorless, odorless liquids, however, have different textures and behaviors when heated. PG, being more fluid, is distinguished by its ability to carry flavors and produce what vapers call the "throat hit," that characteristic sensation in the throat when inhaling, according to technical data available on PG/VG compositions. VG, being more viscous and slightly sweet, produces, conversely, a much denser vapor and a significantly smoother mouthfeel.

This physical difference explains why the choice of the PG/VG/CBD ratio significantly changes the vaping experience, going far beyond a simple matter of preference:

  • PG improves the dissolution of CBD in the liquid, which promotes a more even distribution of the cannabinoid with each puff.
  • VG, being fattier, dissolves CBD less easily but generates a greater volume of vapor.
  • A high proportion of VG accelerates the wear of coils, especially on low-end equipment.
  • PG, in small quantities in some sensitive users, can cause more pronounced throat irritation.

Neither base is inherently "better." It all depends on the priority: faithful reproduction of CBD and flavors, or a vaping experience focused on vapor production. This trade-off determines the most suitable PG/VG/CBD ratio for each consumer profile.

Why CBD solubility depends on the chosen base

CBD is a lipophilic molecule, meaning it dissolves more easily in oily liquids or liquids with a chemical structure similar to its own. Propylene glycol (PG), being less viscous and more chemically compatible, therefore offers better solubility than vegetable glycerin (VG), which is denser and oilier. A base too rich in VG can thus lead to the CBD gradually separating within the bottle, or even to visible crystallization at the bottom of the container.

Signs of a poorly formulated CBD e-liquid:

  • Unusual turbidity or persistent cloudiness after shaking
  • Deposits or crystals visible at the bottom of the bottle
  • Loss of homogeneity between the top and bottom of the liquid
  • Separation into two distinct phases after a few weeks of storage

Pro tip: Before each use, always shake your bottle for about ten seconds. A well-formulated CBD liquid regains its homogeneity almost instantly; if it remains cloudy or grainy after shaking, it's probably a sign of an unstable formulation or an incorrect CBD dosage.

This instability directly impacts dose consistency. If the cannabinoid settles at the bottom, the first few puffs from a new bottle will be underdosed, while the last puffs could deliver a concentration far higher than indicated on the label. Technical analyses of the concentration and base of CBD e-liquids confirm that the choice of base directly influences the accuracy of the actual dosage, not just the vaping experience. This is reason enough to favor laboratory-tested products over unverified, homemade blends.

Example of unstable separation and dosing

What studies say about the ratio, flavor, and vapor production

Experimental studies on e-cigarette emissions shed concrete light on what actually happens when an e-liquid is heated, specifically the effect of the PG/VG ratio on emissions (https://pmc.ncbi.nlm.nih.gov/articles/PMC7453347/). In practical terms, this means that a liquid richer in PG promotes a more intense flavor and a stronger throat hit. Conversely, VG generates particles with a larger average diameter, which increases light scattering and therefore the visibility of the vapor cloud, even if the overall particle mass is lower.

PG/VG ratio Dominant effect observed Typical use
70/30 Higher TPM and flavor yield, pronounced hit CBD extraction and flavors, indirect draw
50/50 Compromise between hit, steam and comfort Versatile use, consumer-grade equipment
30/70 Larger particles, significant visible cloud Direct draft, steam volume search

For a CBD user, this scientific trade-off translates into a very concrete practical question: do you prefer a sensation faithful to the product, with a clear reproduction of the taste and effects felt quickly, or a generous cloud of vapor, even if it slightly dilutes the perception of the cannabinoid? There is no universal answer, but the data confirms that increasing the PG content remains the most consistent approach when the primary objective is the perceived effectiveness of CBD rather than the visual spectacle of the vapor.

What PG/VG ratio should you choose based on your equipment?

The best PG/VG/CBD blend isn't solely a matter of taste preference: the equipment used imposes its own technical constraints. A slim pod or compact pen won't tolerate the same viscosity as a larger mod equipped with low-resistance coils.

  1. 70/30 (PG/VG) : the standard ratio for most CBD e-liquids. It's perfectly suited to pods and mouth-to-lung devices, while ensuring optimal delivery of terpenes and cannabinoids. Practical guides on CBD e-liquids confirm that this ratio is by far the most common in the consumer market, precisely because it facilitates CBD dissolution without compromising throat comfort.
  2. 50/50 A versatile compromise, suitable for most common devices. This PG/VG/CBD ratio limits the risk of excessive irritation while maintaining a satisfactory vapor production.
  3. 30/70 Reserved for cloud chasers and direct lung hitters on mods. However, be aware of the higher viscosity, which causes coils to gunk up more quickly and can reduce their lifespan.

Pro tip: If your VG-dominant CBD e-liquid becomes too thick or flows poorly in your tank, a small amount of propanediol can thin the mixture without increasing the PG content, an interesting option for people sensitive to throat irritation while looking to maintain a proper flow in the device.

No equipment imposes a single possible ratio, but ignoring these technical constraints almost always leads to a disappointing experience: leaks, premature fouling, or impoverished aromatic reproduction.

What PG/VG ratio should you choose based on your equipment? — overview diagram

How to convert and dose CBD in mg/ml and as a percentage

Reading a CBD bottle label requires understanding two units: percentage and mg/ml. The conversion is simple once you grasp the concept. A bottle labeled 300 mg per 10 ml contains a concentration of 30 mg/ml, which is equivalent to 3%, according to the conversion methods detailed for CBD e-liquids. This calculation makes it easy to compare products presented with different labeling formats.

Dosage ranges vary depending on experience level:

  1. Beginner : between 5 and 15 mg/ml. This range allows you to observe the effects without overloading the body from the first uses.
  2. Regular use : between 15 and 30 mg/ml, suitable for people already familiar with CBD and looking for a more consistent effect throughout the day.
  3. Confirmed use : 30 mg/ml and above, sometimes up to 50 mg/ml or more, reserved for experienced consumers who have already tested intermediate concentrations.

The dose increase should remain gradual, with a few days of observation between each stage.

What are the risks associated with vaping CBD?

Vaping CBD is not without risk, even when the product complies with legal THC limits. An assessment conducted for the WHO FCTC shows that PG and VG concentrations measured after a single puff can exceed certain thresholds for airway irritation, according to this report on the potential effects of inhaling nicotine-free vapor. This irritation therefore depends not only on the CBD itself, but also on the base in which it is carried.

The most documented risk, however, remains linked to contaminants, and not to PG/VG bases as such.

An experimental study showed that adding CBD oil and vitamin E acetate to an aerosol can accumulate on the bronchial epithelium and cause high cell death after repeated exposures, according to this research on airway epithelial damage. This is precisely the mechanism that has been linked to the EVALI cases reported in the United States.

Other studies also show that highly concentrated CBD distillates present an increased risk of oxidation product formation when heated, according to this study on oxidation products generated when vaping CBD, a phenomenon that proper dilution in a PG/VG base tends to limit.

Taking certain precautions can significantly reduce exposure to these risks:

  • Opt for products that have undergone independent laboratory analysis, with a certificate available for review.
  • Avoid undiluted CBD distillates or those of uncertain origin.
  • Limit excessive heating temperatures on your device.
  • Pregnant women and people with respiratory conditions should refrain from using this product and consult a healthcare professional before use.

Mix, store and maintain your equipment

A poorly prepared DIY CBD e-liquid quickly loses quality, whether due to inadequate mixing or improper storage. Here's how to minimize these problems.

  1. Homogenize the bottle : shake vigorously for about thirty seconds, let it stand for a few minutes, then check the liquid's clarity in the light. A persistent cloudiness indicates a formulation problem.
  2. To dilute a liquid that is too concentrated or too viscous : gradually add a small amount of PG or propanediol, a few drops at a time, shaking again between each addition to avoid any local over-accumulation of CBD.
  3. Coil maintenance : High-VG bases cause coils to gunk up faster. Plan to replace them more frequently than with a standard e-liquid, and watch out for any burnt taste, a telltale sign of a worn-out coil.

Pro tip: For DIY isolate-based blends, gently warming the mixture in a double boiler before adding the CBD helps it dissolve. Then let it cool completely and shake well before use; this significantly reduces the risk of crystallization.

What Thefrenchhempempire guarantees about its vape products

Choosing a reliable PG/VG/CBD e-liquid requires being able to verify the actual contents of the bottle. Thefrenchhempempire relies on independent laboratory analyses and strictly adheres to the legal limit of 0.3% THC across its entire range. This traceability limits exposure to the undeclared additives mentioned above, particularly vitamin E acetate.

For readers wishing to avoid the uncertainties of DIY mixing, the CBD vape range offers pre-balanced PG/VG formulations, ready to use. Those interested in an even more stable solution in terms of dosage can also consult the guide on criteria for recognizing quality CBD, which details the points to check before making a purchase.

This information is for educational purposes only and in no way replaces personalized medical advice.

The key takeaways when choosing the ratio

Caution should always prevail over improvisation when it comes to inhaling anything, even a product as regulated as CBD. Before making a purchase, always check for an independent certificate of analysis: it's the only reliable way to know what a bottle actually contains, beyond marketing claims. For the vast majority of users, a 70/30 or 50/50 ratio remains the most sensible choice, as it limits the risk of instability while maintaining proper cannabinoid absorption. Pregnant women, people with respiratory problems, or complete beginners should adopt a particularly gradual approach, always starting with the lowest available dosages.

— Vanessa

Find a traceable and compliant CBD e-liquid

A well-formulated CBD e-liquid isn't something you can just throw together, and buying blindly is the surest way to end up with an unstable or poorly dosed product. Some shops offer vapes and cartridges that are already balanced in PG/VG, often accompanied by independent lab analyses that can be consulted before purchase.

Thefrenchhempempire

For vapers who want a ready-to-use solution without worrying about solubility or crystallization, the 1ml Vape FTS Pure Extract CBD offers a stable, pre-strengthened formulation. Those who prefer a cartridge compatible with their own device can opt for the 510 CBD Full Spectrum cartridges. Before ordering, take the time to review the certificate of analysis associated with each product on the dedicated CBD vape page: it's the best guarantee against unpleasant surprises.

Sources

To delve deeper into the mechanisms mentioned, several references remain essential: the WHO FCTC report on the potential effects of vapor inhalation, the study on damage to the airway epithelium linked to vitamin E acetate, the work of Talih et al. on the effect of the PG/VG ratio on emissions, as well as the analysis of oxidation products formed during CBD vaping.

This article provides general information and is not a substitute for professional medical advice. Consult a qualified healthcare professional about your specific situation before taking any action based on this content.

Frequently Asked Questions

What PG/VG ratio should I choose for a CBD e-liquid?

For most users, a 70/30 or 50/50 (PG/VG) ratio offers the best balance between CBD absorption, flavor delivery, and throat comfort. The final choice depends primarily on the equipment used and the desired priority between flavor and vapor production.

What is the recommended CBD level for an e-liquid?

Beginners generally prefer a concentration between 5 and 15 mg/ml, while regular users often go up to between 15 and 30 mg/ml. Experienced users can reach 30 mg/ml or more, provided they have progressed in successive stages.

80/20 or 50/50: which ratio should you choose for an e-liquid?

A high PG ratio strongly enhances throat hit and flavor delivery, but also increases the risk of irritation for some sensitive users. A 50/50 ratio is often preferable for versatile daily use, as it moderates this sensation while maintaining a decent vapor production.

Which CBD liquid is the most potent?

The perceived potency depends more on the concentration in mg/ml than on the PG/VG ratio itself: a 50 mg/ml bottle will deliver a stronger effect than a 15 mg/ml bottle, regardless of the base used. It's better to choose a product that has been lab-tested, like those offered by Thefrenchhempempire, rather than relying solely on a number on the label.

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Vanessa

I'm Vanessa, a writer specializing in topics related to hemp, CBD, and legal cannabis. For several years, I've been interested in market trends, cannabinoids, French and European regulations, and the challenges of quality, traceability, and safety for consumers. Through my articles, my goal is to provide clear, verified, and accessible information to help everyone better understand the world of CBD and hemp-derived products. Each article is written using official, scientific, or regulatory sources when the topic requires it.